Postdoctoral Associate in Molecular and Cellular Biology of Membrane Lipids
Postdoctoral Associate in Molecular and Cellular Biology of Membrane Lipids
Description: Join the Hammond lab at the University of Pittsburgh department of Cell Biology as a post-doc and spearhead a groundbreaking project that uncovers the secrets of membrane lipid signaling, amplifying our understanding of cellular physiology and disease. We have made recent groundbreaking discoveries regarding how the central regulatory lipid, PI(4,5)P2, regulates myriad aspects of cellular physiology at the plasma membrane. By investigating how this lipid is balanced and exploring its impact on cellular function, you will have the opportunity to unravel the mechanisms behind diseases ranging from cancer to dysentery. A current particular focus is on the lipid's dynamics in metastatic breast cancer. As a key member of our team, you will pioneer research to identify the regulatory pathways that maintain lipid levels and explore the molecular landscape constraining its dynamics. This is expected to lead towards the development of innovative strategies for restoring lipid balance in disease. Visit hammondlab.com to explore more details of our research. Don't miss out on this incredible opportunity to make a profound impact on human health and advance scientific knowledge. The earliest start date is 7/1/2023, with flexibility based on your circumstances, such as the completion of your thesis work.
Responsibilities:
- The candidate will be 100% focused on research and professional development activities.
- The candidate will use the lab's main approach using single-cell technology with in-house state-of-the-art fluorescence and single molecule imaging to track lipid function in single, living cells.
- This is performed on cells experimentally manipulated using and array of innovative gene-editing and synthetic biology approaches.
- Supporting novel lipid biochemical approaches will also be studied
- Development of novel hypotheses and independent research directions will be a goal of this position, with the goal of launching the applicant into an independent position in academia or industry.
Qualifications:
- A Ph.D. in Cell Biology is essential.
- The applicant should have 4 or more years' experience with basic cell biology approaches, including
- molecular biology
- advanced fluorescence microscopy
- cell culture.
- Experience in gene editing and/or coding in python and ImageJ are highly desired.
Opportunities
- Publish first author papers in high impact cell biology journals
- Attend at least one international conference in lipid biology
The University of Pittsburgh is an Affirmative Action/ Equal Opportunity Employer and values equality of opportunity, human dignity and diversity, EOE, including disability/vets.
Apply online at https://cfopitt.taleo.net/careersection/pitt_faculty_external_pd/jobdetail.ftl?job=23003909&tz=GMT-04%3A00&tzname=America%2FNew_York, including a cover letter detailing how you research interests and goals fit with the lab's, and a CV. Salaries start at $56,484.